Science for the long game
Geroprotect Blog
Spermidine: The Molecule Your Gut Bacteria Make, and What the Human Studies Actually Show
Reviewed explainer Spermidine is a small molecule called a polyamine. Your cells make it, your food contains it, and a new study in fruit flies shows that gut…
Spermidine Supplement UAE: Reading the Label, Dose and Source
UAE buying guide If you are comparing a spermidine supplement in the UAE, you will often meet two labels that look nothing alike: one lists spermidine in milligrams,…
Ca-AKG supplement UAE: a label checklist
UAE buying guide This is a label-first checklist for a Ca-AKG supplement in the UAE. It explains what alpha-ketoglutarate is, why the calcium-bound form is printed on the…
Urolithin A supplement UAE: what the label must show before you buy
UAE buying guide This urolithin A supplement UAE guide explains what the label must show before you buy, and how to check the measured amount rather than the…
NMN supplement UAE: read the label, dose and certificate first
UAE buying guide This NMN supplement UAE guide starts with the label, not the headline. It explains what to check on any label before you compare prices, walks…
Healthy Ageing Supplements in Dubai: A Label-First Checklist
UAE buying guide Buying healthy ageing supplements in Dubai often means comparing long lists of ingredients that are hard to measure side by side. This guide gives you…
Geroprotect UAE: delivery, prices in AED and where to buy
UAE buying guide This Geroprotect UAE guide covers the two tablet formulas, their prices in AED, free delivery across all seven emirates, returns and where to buy. Geroprotect®…
What are the best healthy-aging supplements in 2026?
How to judge a healthy-aging stack: full dose disclosure, evidence tiers, certificates and cost per day — with the 13-active Essentials I measured.
What is the best NMN supplement in 2026?
How to read an NMN label: the exact molecule and dose, purity certificates and honest NAD+ evidence — with Essentials I measured against the same checklist.
What is the best Urolithin A supplement in 2026?
How to read a Urolithin A label: real Urolithin A versus pomegranate precursors, exact doses, certificates and honest evidence — with Essentials I measured.
What is the best Ca-AKG supplement in 2026?
How to read a Ca-AKG label: exact dose per serving, the calcium-bound form, third-party certificates and honest human evidence — with Essentials I measured against the same checklist.
Withaferin A Is Not Total Withanolides: The 18 mg Specification
A calm specification review of Withaferin A, ashwagandha extract and total withanolides—plus the conditional arithmetic behind the current 18 mg formula declaration.
Resveratrol After the Hype: Human Trials, SIRT1 and Bioavailability
A primary-source review of resveratrol: mixed human metabolic trials, rapid conjugation, the qualified SIRT1 story, a normal-diet mouse lifespan null and proportionate safety context.
Pentadecanoic Acid (C15:0): Human Trials, Essentiality and Causal Limits
A primary-source review of C15:0: what two human trials found, why essentiality and blood-threshold claims remain unsettled, how observational and Mendelian-randomisation results differ, and what 240 mg in…
The Fourth Hydroxyl: Luteolin, Mast Cells, CD38 and the Human Evidence Gap
A primary-source review of luteolin: the published pure-luteolin null, combination trials, mast-cell and CD38 mechanisms, worm lifespan, ferroptosis, safety and formula boundaries.
Ca-AKG: From the TCA Cycle to the Epigenetic Clock
A primary-source review of Ca-AKG: TCA-cycle and dioxygenase biology, uncontrolled and observational human clock data, the pending ABLE trial, bone turnover, conflicting mouse lifespan studies and formula limits.
TUDCA: A Bile Acid at the Proteostasis Frontier
An evidence-led review of TUDCA: bile-acid identity, human metabolic and liver trials, proteostasis mechanisms, direct TUDCA and AMX0035 ALS results, safety and formula boundaries.
The Purity Dogma
Purity is a specification, not an efficacy result: a primary-source framework using curcumin, ginseng and fucoidan to separate identity, exposure and clinical evidence.
Six Hundred and Twenty
A preparation-specific review of 620 MS-assigned ginsenosides, compound K, microbiome variation, worm longevity, stem-cell models, human trials and the meaning of an 80% label.
Ninety-Eight Percent of What?
A preparation-specific review of fucoidan chemistry, the small human trial record, SIRT6 and senescence research, oral haemostasis evidence and the supplier details still needed.
Nattokinase: Measure the Enzyme, Not Just the Milligrams
A preparation-specific review of nattokinase: what FU measures, what controlled human trials found, why PAI-1 remains a mechanistic hypothesis and which product documents still matter.
EGCG: Green Tea’s Most Studied Catechin
A calibrated review of EGCG: human pharmacokinetics, mixed metabolic trials, molecular mechanisms, food state and the dose-contextualised green-tea-extract liver signal.
CoQ10: Energy in Motion
A calibrated review of CoQ10: mitochondrial electron transfer, formulation-dependent exposure, Q-SYMBIO, the selenium-plus-CoQ10 KiSel-10 trial, mixed human outcomes and the current 150 mg formula context.
The Root That Learned It Twice
A critical review of baicalein: four Phase I publications, ALOX12 and ferroptosis, alpha-synuclein, senescence, invertebrate longevity and the evidence that is still missing.
L-Ergothioneine: The Diet-Derived ‘Longevity Vitamin’?
A critical review of L-ergothioneine: SLC22A4 transport, human pharmacokinetics, mortality and cognitive cohorts, primary-null trial evidence, preclinical mechanisms and regulatory limits.
Fuel Without a Furnace
A critical review of NAD+ precursors and mitophagy, separating human trials from mechanism, nulls and commercial conflicts.
From Coptis to the Clock
Berberine has human metabolic data. AKG has an elegant mechanism — and a rigorous 2026 mouse lifespan null. Here is the complete evidence boundary.
Clear, Quiet, Spare
Fisetin, quercetin and apigenin are not interchangeable. Human trials exist; this review separates their endpoint-specific results from unproven human senolysis and finished-formula efficacy.
What Are Geroprotectors? From Research Category to Responsible Claim
Geroprotectors are candidate interventions studied for effects on aging and healthspan. The label is a research hypothesis until strong human outcomes support it.
Why Do We Age? Evolution, Maintenance and the Biology Between
Why aging exists is an evolutionary question; how it unfolds is a cellular one. Together they explain why damage, signalling and repair all matter.
Uncovering the Aging Process: Signals, Clocks and Causality
Aging leaves measurable molecular patterns. This guide separates inflammation, epigenetic clocks and reprogramming experiments from claims they cannot yet support.
What Are Senolytics? Promise, Precision and the Human Evidence Gap
Senolytics are designed to remove selected senescent cells. The animal evidence is compelling; human efficacy and the relevance of supplement doses remain open questions.
The Hallmarks of Aging: A Map, Not a Scorecard
A clear guide to the canonical twelve hallmarks of aging, the two emerging mechanisms in Geroprotect’s educational map, and what a hallmark can—and cannot—prove.
